Antioxidant Vitamins and Health:
Cardiovascular Disease, Cancer, Cataracts, and Aging

Claude Fernand Bourgeois

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September 2003
310 pp.
ISBN: 0-9664286-6-8

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The idea for this book originated from a request by the French organization for trade, Direction Genrale de la Concurrence, de la Consommation et de la R

The book begins with a discussion of free radicals and the reactive oxygen species generated in vivo, goes on to describe the mechanism of antioxidation and the antioxidant defenses in humans, and reviews epidemiological studies carried out over the past two decades. These are thoroughly discussed and compared, and conclusions drawn.

The book covers primarily vitamins C and E and b-carotene, as well as polyphenols. These are the antioxidants with which most studies are concerned. It does not discuss mineral antioxidant nutrients nor other vitamins.

Oxidative phenomena have been implicated in about 50 pathologies! The coverage in this book is limited to the four most studied: cardiovascular disease, cancer, cataracts, and aging (allowing aging to be considered as a pathology). While summarizing numerous published studies, the book also offers more general information to researchers interested in these antioxidant nutrients and, it is hoped, points toward areas for future research.

The book will appeal to researchers in the fields of antioxidant, cardiovascular disease, cancer, cataracts, and aging; nutritional and pharmaceutical scientists; and students in these disciplines.

I thank Lucien Cronenberger, Pierre Mainguy, and Marc Nicol, who reviewed the whole manuscript, and the specialists who reviewed individual chapters: Bruno Lesourd, Henri Lestradet, Maurice Tubiana, In-Birlouez-Aragon, Jean Claude Guilland, and Marc Suschetet. I also thank the technical board members of CEDAP. I thank Mrs. Liliane Rougemont for help in typing the manuscript. And finally, I thank Mr. Paul Finglas (A.F.R.C. Food Research Institute, Norwich, U.K.), who kindly corrected my English.

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